UKpurineclub.org

2nd UK Purine Symposium (Registration is now closed)

Friday 17th September 2010, 10:00-18:00.

Jubilee 
campus

Business School South, Jubilee Campus, University of Nottingham

We are pleased to announce that the 2nd UK Purine Symposium will be held at the Jubilee Campus, University of Nottingham on Friday 17th September 2010.

Programme to include:
 
Plenary lectures from:
Oral and poster communications
 

Professor Geoff Burnstock, UCL
Professor Steve Hill, Nottingham
Professor Richard Evans, Leicester

Professor Ad IJzermann, Leiden-Amsterdam

Lunch, wine reception and poster viewing
Conference dinner

This symposium will bring together researchers from all over the UK interested in purine research. The emphasis of the meeting is to highlight the breadth of purine research in the UK and to stimulate lively discussion and an exchange of ideas. The abstract booklet is available here. These abstracts will be published in the prestigious journal Purinergic Signalling.

We look forward to seeing you in Nottingham! Vera Ralevic & Steve Alexander (Meeting Organisers)

Directions and accommodation information are available here. Any enquiries about the meeting? Email info@ukpurineclub.org.

Note that Sarissa have a workshop on Monday 27th September at the University of Warwick. You can register for the workshop using a pdf or MS-Word document.

Some recent publications on:

Adenosine receptors

Mlejnek, P. and Dolezel, P. (2010) Induction of apoptosis by A3 adenosine receptor agonist N6-(3-iodobenzyl)-adenosine-5'-N-methylcarboxamide in human leukaemia cells: a possible involvement of intracellular mechanism Acta Physiologica 199 (2) 171-179 Link to abstract

P2 receptors

Chen, X.Y., Pierce, B., Naing, W., Grapperhaus, M.L., and Phillion, D.P. (2010) Discovery of 2-chloro-N-((4,4-difluoro-1-hydroxycyclohexyl)methyl)-5-(5-fluoropyrimid in-2-yl)benzamide as a potent and CNS penetrable P2X7 receptor antagonist Bioorganic & Medicinal Chemistry Letters 20 (10) 3107-3111 Link to abstract

Transporters

Knight, D., Harvey, P.J., Iliadi, K.G., Klose, M.K., Iliadi, N., Dolezelova, E., Charlton, M.P., Zurovec, M., and Boulianne, G.L. (2010) Equilibrative nucleoside transporter 2 regulates associative learning and synaptic function in Drosophila J Neurosci 30 (14) 5047-5057 Link to abstract

Enzymes

Sowa, N.A., Voss, M.K., and Zylka, M.J. (2010) Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation Mol Pain 2010 6 (1) 20- Link to abstract

Sponsored by:
(clickable links)

Tocris

Ascent Scientific

Sarissa

Bioline

Adenosine receptors

P2X receptors

P2Y receptors

Previously highlighted publications on:

Adenosine receptors

Lerner TN, Horne EA, Stella N, Kreitzer AC (2010). Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. Journal of Neuroscience 30: 2160-2164. Link to abstract

P2 receptors

Chen XW, Molliver DC, Gebhart GF (2010). The P2Y2 receptor sensitizes mouse bladder sensory neurons and facilitates purinergic currents. Journal of Neuroscience 30: 2365-2372. Link to abstract

Transporters

Redzic ZB, Malatiali SA, Grujicic D, Isakovic AJ (2010). Expression and functional activity of nucleoside transporters in human choroid plexus. Cerebrospinal Fluid Res 7: 2. Link to abstract

Enzymes

Hoeglund AB, Bostic HE, Howard AL, Wanjala IW, Best MD, Baker DL et al. (2010). Optimization of a pipemidic acid autotaxin inhibitor. Journal of Medicinal Chemistry 53: 1056-1066. Link to abstract